The cytocentrifuge NBT test.

The cytocentrifuge NBT test.

The NBT test is a non-specific test of neutrophil membrane stimulation which has application to the study of neutrophil function, particularly in the septicaemic patient. An improved cytochemical test which eliminates potential sources of laboratory error has been developed. Venous or capillary blood samples may be studied and the technique can be applied to the neutropenic patient since availa...

Sickle cell anaemia and the NBT test.

Patients with sickle cell anaemia have an increased susceptibility to bacterial infections Previous reports of false-negative nitro blue tetrazolium (NBT) tests in the presence of bacteria infection and of a faulty phagocytic response following stimulation in vitro have suggested the possibility of polymorphonuclear dysfunction in certain patients with sickle cell anaemia. In the present study ...

Chronic Granulomatous Disease and the Nttroblue Tetrazolium (nbt) Test

Chronic granulomatous disease (CGD) is a congenital disorder characterized by severe and recurrent infections, including pneumonia and deep tissue abscesses, leading to early death from sepsis. (Curnutte and Babior 1987). Two forms of inheritance have been noted. Most cases (80-90%) show X-linked transmission, with the remaining cases being autosomal recessive. Both forms have in common a defic...

The nitroblue tetrazolium (NBT) test in renal transplantation.

The nitroblue tetrazolium (NBT) test has been evaluated as a means of differentiating episodes of infection and rejection in 10 cadaver kidney transplant recipients. Normal NBT values were observed during all 11 episodes of acute rejection. A significant elevation of the NBT score was encountered in six of eight episodes of infection after transplantation. A positive NBT result is useful additi...

Infective complications of open-heart surgery and the monitoring of infections by the NBT test.